Gavin Stewart Dawe

Ph.D
Associate Professor, Department of Pharmacology
National University of Singapore
16 Medical Drive, #04-01Y, Singapore 117600
Tel: +65 6516 8864
Email: gavindawe@nus.edu.sg / gavin_dawe@nuhs.edu.sg

                      

Major Research Interests

  • Neural stem cells and neurogenesis
  • Neurobiology of amyloid precursor protein (APP)
  • Neuropsychopharmacology of antipsychotics and antidepressants

Recent Publications

Young JW, Ratty A, Dawe GS, Geyer MA. Altered exploration and sensorimotor gating of the chakragati mouse model of schizophrenia. Behav Neurosci. 2014 Aug;128(4):460-7.

Loo LS, Tang N, Al-Haddawi M, Dawe GS, Hong W. A role for sorting nexin 27 in AMPA receptor trafficking. Nat Commun. 2014;5:3176.

Lee LC, Rajkumar R, Dawe GS. Selective lesioning of nucleus incertus with corticotropin releasing factor-saporin conjugate. Brain Res. 2014 Jan 16;1543:179-90.

Farooq U, Rajkumar R, Sukumaran S, Wu Y, Tan WH, Dawe GS. Corticotropin-releasing factor infusion into nucleus incertus suppresses medial prefrontal cortical activity and hippocampo-medial prefrontal cortical long-term potentiation. Eur J Neurosci. 2013 Aug;38(4):2516-25.

Rajkumar R, Suri S, Deng HM, Dawe GS. Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to induce long-lasting potentiation in the rat hippocampus. Hippocampus. 2013 Jul;23(7):616-24.

Rajkumar R, See LK, Dawe GS. Acute antipsychotic treatments induce distinct c-Fos expression patterns in appetite-related neuronal structures of the rat brain. Brain Res. 2013 May 1;1508:34-43.

Sundaram JR, Poore CP, Sulaimee NH, Pareek T, Asad AB, Rajkumar R, Cheong WF, Wenk MR, Dawe GS, Chuang KH, Pant HC, Kesavapany S. Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo. J Neurosci. 2013 Jan 2;33(1):334-43.

Dawe GS, Nagarajah R, Albert R, Casey DE, Gross KW, Ratty AK. Antipsychotic drugs dose-dependently suppress the spontaneous hyperactivity of the chakragati mouse. Neuroscience. 2010 Nov 24;171(1):162-72.

Lim EP, Tan CH, Jay TM, Dawe GS. Locus coeruleus stimulation and noradrenergic modulation of hippocampo-prefrontal cortex long-term potentiation. Int J Neuropsychopharmacol. 2010 Oct;13(9):1219-31.

Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, Karagogeos D, Watanabe K, Dawe GS, Xiao ZC. A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat Cell Biol. 2008 Mar;10(3):283-94.