Ling Hua
Research Assistant Professor
Department of Biochemistry, Yong Loo Lin School of Medicine
Principal Investigator, NUS SynCTI
Tel: +65 6601 2449
Email: bchlingh@nus.edu.sg

What are your present research interests?

My research interests lie in engineering of microorganisms for producing value-added compounds and executing target functionalities.

Do you have a distinctive viewpoint to your research?

Through synthetic biology, we envisage to offer solutions to address industrial, agricultural and medical challenges.

What do you see as your future research directions?

We are passionate to apply synthetic biology principles for precision cellular design, which will enable cost-effective and sustainable production of bioproducts for industrial and healthcare applications.

Does your laboratory have a particularly strong research expertise?

Our domain expertise lies in designing combinatorial engineering strategies to construct microbial strains with desirable phenotypes. We are also well-versed in metabolic pathway reconstruction and optimization of E. coli, yeast, and probiotics.

Recent Publications

1. Ling H, Pratomo Juwono NK, Teo WS, et al. (2015) Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae. Biotechnol Biofuels, 8: 231.
MS-based lipidomics of human blood plasma – a community-initiated position paper to develop accepted guidelines. Journal of Lipid Research, 2018, 59(10), 2001-2017.
2. Teo WS, Ling H, Yu AQ, et al. (2015) Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel. Biotechnol Biofuels, 8:177.
3. Ling H, Teo WS, Chen B, et al. (2014) Microbial tolerance engineering toward biochemical production: from lignocellulose to products. Curr Opin Biotechnol, 29C:99-106.
4. Ling H, Chen BB, Kang A, et al. (2013) Transcriptome response to alkane biofuels in Saccharomyces cerevisiae: identification of efflux pumps involved in alkane tolerance. Biotechnol Biofuels, 6:95.