Maybelle Darlene Kho Go
Research Assistant Professor
Department of Biochemistry, Yong Loo Lin School of Medicine
Principal Investigator, NUS SynCTI
Tel: +65 6601 2449
Email: bchmdkg@nus.edu.sg

What are your present research interests?

Characterization of enzymes for therapeutic and commercial applications.

Do you have a distinctive viewpoint to your research?

I would like to develop synthetic biology as a central scientific discipline.

What do you see as your future research directions?

I would like to harness nature’s tools to create greener technologies.

Does your laboratory have a particularly strong research expertise?

We have developed methodologies to characterize enzymes for a wide variety of applications.

Recent Publications

1. Go, MK; Zhao, LN; Xue, B; Supekar, S; Robinson, RC; Fan, H; Yew, WS. Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily. Structure. 2020, 28 (6), 635–642.E3.
2. Chua, JPS; Go, MK; Osothprarop, T; Mcdonald, S; Karabadzhak, AG; Yew, WS; Peisajovich, S; Nirantar, S. Evolving a Thermostable Terminal Deoxynucleotidyl Transferase. ACS Synth Biol. 2020, 9 (7), 1725–1735.
3. Liow, LT; Go, MK; Chang, MW; Yew, WS. Toolkit Development for Cyanogenic and Gold Biorecovery Chassis Chromobacterium violaceum. ACS Synth Biol. 2020, 9 (4), 953–961.
4. Yew, WS; Liow, LT; Go, M. Characterization of Constitutive Promoters from the Anderson library in Chromobacterium violaceum ATCC 12472. Engineering Biology. 2019.