Teo Yik-Ying
D. Phil. (Oxford)
Professor, Saw Swee Hock School of Public Health
Associate Faculty Group Leader, Genome Institute of Singapore
Programme Leader, Singapore Integrative Omics Programme (iOmics)
Blk MD3, 16 Medical Drive, NUS, Singapore 117597
Tel: +65 6516 2760
Email: ephtyy@nus.edu.sg

 
Major Research Interests

Understanding the genetic basis of population diversity, drug responses, complex traits and common diseases. Integrative analyses of omics technologies in genomics, transcriptomics and lipidomics with clinical and environmental factors.

• Positive Darwinian selection in humans and infectious disease pathogens
• Methodologies for genetic association studies with genome-wide genotyping and exome-sequencing
• Population-level whole-genome sequence analysis
• Pharmacogenomics and pharmacodiagnostics
• Genomic diversity across Asian populations and the implications to public health

Recent Publications

1. Takeuchi F, Katsuya T, Kimura R, Nabika T, Isomura M, Ohkubo T, Tabara Y, Yamamoto K, Yokota M, Liu X, Saw WY, Mamatyusupu D, Yang W, Xu S; Japanese Genome Variation Consortium, Teo YY, Kato N. The fine-scale genetic structure and evolution of the Japanese population. PLOS One: 12:e0185487. 2017
2. Yew CW, Lu D, Deng L, Wong LP, Ong RT, Lu Y, Wang X, Yunus Y, Aghakhanian F, Mokhtar SS, Hoque MZ, Voo CL, Abdul Rahman T, Bhak J, Phipps ME, Xu S, Teo YY, Kumar SV, Hoh BP. Title of article: Genomic structure of the native inhabitants of Peninsular Malaysia and North Borneo suggests complex human population history in Southeast Asia. Human Genetics: 137:161-173. 2018
3. Holt KE, McAdam P, Thai PVK, Thuong NTT, Ha DTM, Lan NN, Lan NH, Nhu NTQ, Hai HT, Ha VTN, Thwaites G, Edwards DJ, Nath AP, Pham K, Ascher DB, Farrar J, Khor CC, Teo YY, Inouye M, Caws M, Dunstan SJ. Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam. Nature Genetics: 50:849-856. 2018