Selected Publications


  1. Yason JA, Liang YR, Png CW, Zhang Y, Tan KSW. Interactions between a pathogenic Blastocystis subtype and gut microbiota: in vitro and in vivo studies. Microbiome 7:30. (2019)
  2. Kalia NP, Hasenoehrl EJ, Rahman NB, Koh VH, Ang MLT, Sajorda DR, Hards K, Grüber G, Alonso S, Cook GM, Berney M, Pethe K. Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection. Proceedings of the National Academy of Sciences of the United States of America 114(28): 7426-7431. (2018)
  3. Too IHK, Bonne I, Tan EL, Chu JJH, Alonso S. Prohibitin plays a critical role in Enterovirus 71 invasion of the central nervous system. PLoS Pathogens 14(1): e1006778. (2018)
  4. Lim HY, Lim SY, Tan CK, Thiam CH, Goh CC, Carbajo D, Chew SHS, See P, Chakarov S, Wang XN, Lim LH, Johnson LA, Lum J, Fong CY, Bongso A, Biswas A, Goh C, Evrard M, Yeo KP, Basu R, Wang JK, Tan Y, Jain R, Tikoo S, Choong C, Weninger W, Poidinger M, Stanley RE, Collin M, Tan NS, Ng LG, Jackson DG, Ginhoux F, Angeli V. Hyaluronan receptor LYVE-1-expressing macrophages maintain arterial tone through Hyaluronan-mediated regulation of smooth muscle cell collagen. Immunity 49(2): 326-341. (2018)
  5. Hertzog BB, Kaufman Y, Biswas D, Ravins M, Ambalavanan P, Wiener R, Angeli V, Chen SL, Hanski E. A sub-population of Group A Streptococcus elicits a population-wide production of bacteriocins to establish dominance in the host. Cell Host & Microbe 23(3): 312-323. (2018)
  6. Dharmadhikari B, Zeng Q, Wu M, Schwarz H. Anti-CD137 cancer immunotherapy suppresses tumor growth—letter. Cancer Research 78(6): 1571. (2018)
  7. Park H-Y, Tan PS, Kavishna R, Ker A, Lu J, Chan CEZ, Hanson BJ, MacAry PA, Caminschi I, Shortman K, Alonso S, Lahoud MH. Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells. NPJ Vaccines 2: 31. (2017)
  8. Mei Y, Zhao L, Liu Y, Gong H, Song Y, Lei L, Zhu Y, Jin Z, Ma S, Hu B, Sun Q, Liu H. Combining DNA vaccine and AIDA-1 in attenuated Salmonella activates tumor-specific CD4+ and CD8+ T-cell responses. Cancer Immunology Research 5(6): 503-514. (2017)
  9. Ichise H, Nagano S, Maeda T, Miyazaki M, Miyazaki Y, Kojima H, Yawata N, Yawata M, Tanaka H, Saji H, Masuda K, Kawamoto H. NK cell alloreactivity against KIR-ligand-mismatched HLA-haploidentical tissue derived from HLA haplotype-homozygous iPSCs. Stem Cell Reports 9(3): 853-867. (2017)
  10. Cho SSL, Han J, James SJ, Png CW, Weerasooriya M, Alonso S, Zhang Y. Dual-specificity Phosphatase 12 targets p38 MAP Kinase to regulate macrophage response to intracellular bacterial infection. Frontiers in Immunology 8: 1259. (2017)
  11. Chua YL, Liong KH, Huang C-H, Wong HS, Zhou Q, Ler SS, Tang Y, Low CP, Koh HY, Kuo I-C, Zhang Y, Wong WSF, Peh HY, Lim HY, Ge MQ, Haczku A, Angeli V, MacAry PA, Chua KY, Kemeny DM. Blomia tropicalis-specific TCR transgenic Th2 cells induce inducible BALT and severe asthma in mice by an IL-4/IL-13-dependent mechanism. Journal of Immunology 197(10): 3771-3781. (2016)
  12. Chionh YH, McBee M, Babu IR, Hia F, Lin W, Zhao W, Cao J, Dziergowska A, Malkiewicz A, Begley TJ, Alonso S, Dedon PC. tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence. Nature Communications 7: 13302. (2016)
  13. Arora S, Lim w, Bist P, Perumalsamy R, Lukman HM, Li F, Welker LB, Yan B, Sethi G, Tambyah PA, Fairhurst A-M, Alonso S, Lim LHK. Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis. Cell Death and Differentiation 23: 1243–1256. (2016)
  14. Chai EZP, Shanmugam MK, Arfuso F, Dharmarajan A, Wang C, Kumar AP, Perumalsamy R, Lim LHK, Wang L, Goh BC, Ahn KS, Hui KM, Sethi G. Targeting transcription factor STAT3 for cancer prevention and therapy. Pharmacology & Therapeutics 162: 86-97. (2016)
  15. Zhang J, Ahn KS, Kim C, Shanmugam MK, Siveen KS, Arfuso F, Perumalsamy R, Deivasigamanim A, Lim LHK, Wang L, Goh BC, Kumar AP, Hui KM, Sethi G. Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model. Antioxidants & Redox Signaling 24(11): 575–589. (2016)
  16. Lin D, Lei L, Liu Y, Zhang Y, Hu B, Bao G, Song Y, Jin Z, Liu C, Mei Y, Sandikin D, Wu Y, Zhao L, Yu X, Liu H. Membrane IL-1α inhibits the development of hepatocellular carcinoma via promoting T and NK cell activation. Cancer Research 76(11): 3179-3188. (2016)
  17. Rajendran S, Ho WT, Schwarz H. CD137 signaling in Hodgkin and Reed-Sternberg cell lines induces IL-13 secretion, immune deviation and enhanced growth. OncoImmunology 5(6): e1160188-92. (2016)
  18. Yawata N, Selva KJ, Liu Y-C, Tan KP, Lee AWL, Siak J, Lan W, Vania M, Arundhati A, Tong L, Li J, Mehta JS, Yawata M. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunology 9: 159-170. (2016)
  19. Bian Z, Shi L, Guo Y-L, Lu Z, Tang C, Niu S, Tremblay A, Venkataramani M, Culpepper C, Li L, Zhou Z, Mansour A, Zhang Y, Gewirtz A, Kidder K, Zen K, Liu Y. CD47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells. Proceedings of the National Academy of Sciences of the United States of America 113(37): E5434-E5443. (2016)
  20. Png CW, Weerasooriya M, Guo J, James SJ, Poh HM, Osato M, Flavell RA, Dong C, Yang H, Zhang Y. DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis. Oncogene 35: 206–217. (2016)
  21. Blocki A, Wang Y, Koch M, Goralczyk A, Beyer S, Agarwal N, Lee M, Moonshi S, Dewavrin J-Y, Peh P, Schwarz H, Bhakoo K, Raghunath M. Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications. Molecular Therapy 23(3): 510-522. (2015)
  22. Perumalsamy R, Lim LHK. DAMPs and influenza virus infection in ageing. Ageing Research Reviews 24A: 83-97. (2015)
  23. Liu Y, Wu Y, Wang Y, Cai Y, Hu B, Bao G, Fang H, Zhao L, Ma S, Cheng Q, Song Y, Liu Y, Zhu Z, Chang H, Yu X, Sun A, Zhang Y, Vignali DAA, Wu D, Liu H. IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects. Leukemia 29: 939–946. (2015)
  24. Madhukaran SP, Kishore U, Jamil K, Teo BHD, Choolani M, Lu J. Transcriptional Factor PU.1 regulates decidual C1q expression in early pregnancy in human. Frontiers in Immunology 6: 53. (2015)
  25. Robinson LN, Tharakaraman K, Rowley KJ, Costa VV, Chan KR, Wong YH, Ong LC, Tan HC, Koch T, Cain D, Kirloskar R, Viswanathan K, Liew CW, Tissire H, Ramakrishnan B, Myette JR, Babcock GJ, Sasisekharan V, Alonso S, Chen J, Lescar J, Shriver Z, Ooi EE, Sasisekharan R. Structure-guided design of an anti-dengue antibody directed to a non-immunodominant epitope. Cell 162(3): 493-504. (2015)
  26. Angeli V, Harvey NL. Lymphatic vessels at the heart of the matter. Cell Metabolism 22(1): 56-58. (2015)
  27. Malleret B, Li A, Zhang R, Tan KSW, Suwanarusk R, Claser C, Cho JS, Koh EGL, Chu CS, Pukrittayakamee S, Ng ML, Ginhoux F, Ng LG, Lim CT, Nosten F, Snounou G, Rénia L, Russell B. Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes. Blood 125(8): 1314-1324. (2015)
  28. James SJ, Jiao H, Teh H-Y, Takahashi H, Png CW, Phoon MC, Suzuki Y, Sawasaki T, Xiao H, Chow VTK, Yamamoto N, Reynolds JM, Flavell RA, Dong C, Zhang Y. MAPK Phosphatase 5 expression induced by influenza and other RNA virus infection negatively regulates IRF3 activation and Type I Interferon response. Cell Reports 10(10): 1722-1734. (2015)