Dr Dennis Kappei


Dennis Kappei
Assistant Professor, Dept of Biochemistry, YLL School of Medicine, NUS
Principal Investigator, Cancer Science Institute of Singapore (CSI), NUS
Head, Quantitative Proteomics Core, CSI, NUS
Tel: +65 6516 1083
Email: dennis.kappei@nus.edu.sg

What are your present research interests?

Non-coding DNA/RNA, telomeres, protein-nucleic acid interactions, quantitative mass spectrometry and cancer.

Recent Publications

1. Bluhm A., Viceconte N., Li F., Rane G., Ritz S., Wang S., Levin M., Shi Y. Kappei D.#, Butter F.# (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2. Nucleic Acids Research 47: 1896-1907.
2. Tay L.S., Krishnan V., Sankar H., Chong Y.L., Chuang L.S.H., Tan T.Z., Kolinjivadi A.M., Kappei D. Ito Y. (2018) RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Reports 24: 1747-1755.
3. Jahn A.*, Rane G.*, Paszkowski-Rogacz M., Sayols S., Bluhm A., Han C.T., Draskovic I., Londono-Vallejo J.A., Kumar A.P., Buchholz F.#, Butter F.#, Kappei D.# (2017) ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO Reports 18: 929-946.
4. Casas-Vila N.*, Bluhm A.*, Sayols S.*, Dinges N., Dejung M., Altenhein T., Kappei D., Altenhein B., Roignant J.Y., Butter F. (2017) The developmental proteome of Drosophila melanogaster. Genome Research 27: 1273-1285.